Lgr4-mediated Wnt/β-catenin signaling in peritubular myoid cells is essential for spermatogenesis
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منابع مشابه
Lgr4-mediated Wnt/β-catenin signaling in peritubular myoid cells is essential for spermatogenesis.
Peritubular myoid cells (PMCs) are myofibroblast-like cells that surround the seminiferous tubules and play essential roles in male fertility. How these cells modulate spermatogenesis and the signaling pathways that are involved are largely unknown. Here we report that Lgr4 is selectively expressed in mouse PMCs in the testes, and loss of Lgr4 leads to germ cells arresting at meiosis I and then...
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ژورنال
عنوان ژورنال: Development
سال: 2013
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.093641